Adami was born in Bologna and educated at the academia di Brera in Milan where he studied as a draftsman from 1951 to 1954. Early on, he was mostly associated with the Pop Art movement. His first major show in 1962 at the Institute of Contemporary Art in London was quickly followed by an exhibit at Documenta III in Kassel. He also represented Italy at the 1968 Venice Biennale. Nowadays, Adami mostly works in London and Paris.